Traffic is flowing normally again on the westbound 401 near Tilbury.
Chatham-Kent OPP say a nasty three-vehicle crash closed the lanes for about six hours last night.
The crash happened around midnight and involved two cars and a tractor-trailer just west of the Queen’s Line interchange in Tilbury.
One person was taken to hospital with life-threatening injuries, police say.
The collision is under investigation and additional information will be released as it becomes available.
Anyone with information is being urged to contact the Ontario Provincial Police at 1-888-310-1122 or the Chatham-Kent detachment at 519-352-1122.